Tyrosines-740/751 of PDGFRβ contribute to the activation of Akt/Hif1α/TGFβ nexus to drive high glucose-induced glomerular mesangial cell hypertrophy

Eitemau Tebyg

• TGFβ acts through PDGFRβ to activate mTORC1 via the Akt/PRAS40 axis and causes glomerular mesangial cell hypertrophy and matrix protein expression
  gan: Maity, Soumya, et al.
  Cyhoeddwyd: (2020)
• microRNA-181a Downregulates Deptor for TGFβ-induced Glomerular Mesangial Cell Hypertrophy and Matrix Protein Expression
  gan: Maity, Soumya, et al.
  Cyhoeddwyd: (2018)
• Deacetylation of S6 kinase promotes high glucose–induced glomerular mesangial cell hypertrophy and matrix protein accumulation
  gan: Das, Falguni, et al.
  Cyhoeddwyd: (2019)
• Transforming Growth Factor β Integrates Smad 3 to Mechanistic Target of Rapamycin Complexes to Arrest Deptor Abundance for Glomerular Mesangial Cell Hypertrophy
  gan: Das, Falguni, et al.
  Cyhoeddwyd: (2013)
• TGFβ-Induced PI 3 Kinase-Dependent Mnk-1 Activation is Necessary for Ser-209 Phosphorylation of eIF4E and Mesangial Cell Hypertrophy
  gan: DAS, FALGUNI, et al.
  Cyhoeddwyd: (2013)