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TGFβ-Induced PI 3 Kinase-Dependent Mnk-1 Activation is Necessary for Ser-209 Phosphorylation of eIF4E and Mesangial Cell Hypertrophy

Transforming growth factorβ (TGFβ)-induced canonical signal transduction is involved in glomerular mesangial cell hypertrophy; however, the role played by the noncanonical TGFβ signaling remains largely unexplored. TGFβ time-dependently stimulated eIF4E phosphorylation at Ser-209 concomitant with en...

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Detalhes bibliográficos
Main Authors: DAS, FALGUNI, GHOSH-CHOUDHURY, NANDINI, BERA, AMIT, KASINATH, BALAKUNTALAM S., CHOUDHURY, GOUTAM GHOSH
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855027/
https://ncbi.nlm.nih.gov/pubmed/23359369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24327
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