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The “glymphatic” mechanism for solute clearance in Alzheimer’s disease: game changer or unproven speculation?

How solutes and macromolecules are removed from brain tissue is of central importance in normal brain physiology and in how toxic protein aggregates are cleared in neurodegenerative conditions, including Alzheimer’s disease (AD). Conventionally, solute transport in the narrow and tortuous extracellu...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Smith, Alex J., Verkman, Alan S.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5888402/
https://ncbi.nlm.nih.gov/pubmed/29101220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700999
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