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Test of the 'glymphatic' hypothesis demonstrates diffusive and aquaporin-4-independent solute transport in rodent brain parenchyma

Transport of solutes through brain involves diffusion and convection. The importance of convective flow in the subarachnoid and paravascular spaces has long been recognized; a recently proposed ‘glymphatic’ clearance mechanism additionally suggests that aquaporin-4 (AQP4) water channels facilitate c...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Smith, Alex J, Yao, Xiaoming, Dix, James A, Jin, Byung-Ju, Verkman, Alan S
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578736/
https://ncbi.nlm.nih.gov/pubmed/28826498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27679
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