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Test of the 'glymphatic' hypothesis demonstrates diffusive and aquaporin-4-independent solute transport in rodent brain parenchyma

Transport of solutes through brain involves diffusion and convection. The importance of convective flow in the subarachnoid and paravascular spaces has long been recognized; a recently proposed ‘glymphatic’ clearance mechanism additionally suggests that aquaporin-4 (AQP4) water channels facilitate c...

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Publicado en:eLife
Autores principales: Smith, Alex J, Yao, Xiaoming, Dix, James A, Jin, Byung-Ju, Verkman, Alan S
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578736/
https://ncbi.nlm.nih.gov/pubmed/28826498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27679
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