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The “glymphatic” mechanism for solute clearance in Alzheimer’s disease: game changer or unproven speculation?

How solutes and macromolecules are removed from brain tissue is of central importance in normal brain physiology and in how toxic protein aggregates are cleared in neurodegenerative conditions, including Alzheimer’s disease (AD). Conventionally, solute transport in the narrow and tortuous extracellu...

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書目詳細資料
發表在:FASEB J
Main Authors: Smith, Alex J., Verkman, Alan S.
格式: Artigo
語言:Inglês
出版: Federation of American Societies for Experimental Biology 2018
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5888402/
https://ncbi.nlm.nih.gov/pubmed/29101220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700999
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