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The “glymphatic” mechanism for solute clearance in Alzheimer’s disease: game changer or unproven speculation?

How solutes and macromolecules are removed from brain tissue is of central importance in normal brain physiology and in how toxic protein aggregates are cleared in neurodegenerative conditions, including Alzheimer’s disease (AD). Conventionally, solute transport in the narrow and tortuous extracellu...

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Pubblicato in:FASEB J
Autori principali: Smith, Alex J., Verkman, Alan S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5888402/
https://ncbi.nlm.nih.gov/pubmed/29101220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700999
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