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The “glymphatic” mechanism for solute clearance in Alzheimer’s disease: game changer or unproven speculation?

How solutes and macromolecules are removed from brain tissue is of central importance in normal brain physiology and in how toxic protein aggregates are cleared in neurodegenerative conditions, including Alzheimer’s disease (AD). Conventionally, solute transport in the narrow and tortuous extracellu...

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Bibliographische Detailangaben
Veröffentlicht in:FASEB J
Hauptverfasser: Smith, Alex J., Verkman, Alan S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5888402/
https://ncbi.nlm.nih.gov/pubmed/29101220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700999
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