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Network perturbation analysis of gene transcriptional profiles reveals protein targets and mechanism of action of drugs and influenza A viral infection

Genome-wide transcriptional profiling provides a global view of cellular state and how this state changes under different treatments (e.g. drugs) or conditions (e.g. healthy and diseased). Here, we present ProTINA (Protein Target Inference by Network Analysis), a network perturbation analysis method...

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發表在:Nucleic Acids Res
Main Authors: Noh, Heeju, Shoemaker, Jason E, Gunawan, Rudiyanto
格式: Artigo
語言:Inglês
出版: Oxford University Press 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887474/
https://ncbi.nlm.nih.gov/pubmed/29325153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1314
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