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Network perturbation analysis of gene transcriptional profiles reveals protein targets and mechanism of action of drugs and influenza A viral infection

Genome-wide transcriptional profiling provides a global view of cellular state and how this state changes under different treatments (e.g. drugs) or conditions (e.g. healthy and diseased). Here, we present ProTINA (Protein Target Inference by Network Analysis), a network perturbation analysis method...

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Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Noh, Heeju, Shoemaker, Jason E, Gunawan, Rudiyanto
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887474/
https://ncbi.nlm.nih.gov/pubmed/29325153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1314
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