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Network perturbation analysis of gene transcriptional profiles reveals protein targets and mechanism of action of drugs and influenza A viral infection

Genome-wide transcriptional profiling provides a global view of cellular state and how this state changes under different treatments (e.g. drugs) or conditions (e.g. healthy and diseased). Here, we present ProTINA (Protein Target Inference by Network Analysis), a network perturbation analysis method...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Noh, Heeju, Shoemaker, Jason E, Gunawan, Rudiyanto
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887474/
https://ncbi.nlm.nih.gov/pubmed/29325153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1314
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