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Network perturbation analysis of gene transcriptional profiles reveals protein targets and mechanism of action of drugs and influenza A viral infection

Genome-wide transcriptional profiling provides a global view of cellular state and how this state changes under different treatments (e.g. drugs) or conditions (e.g. healthy and diseased). Here, we present ProTINA (Protein Target Inference by Network Analysis), a network perturbation analysis method...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Noh, Heeju, Shoemaker, Jason E, Gunawan, Rudiyanto
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887474/
https://ncbi.nlm.nih.gov/pubmed/29325153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1314
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