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Inferring gene targets of drugs and chemical compounds from gene expression profiles

Motivation: Finding genes which are directly perturbed or targeted by drugs is of great interest and importance in drug discovery. Several network filtering methods have been created to predict the gene targets of drugs from gene expression data based on an ordinary differential equation model of th...

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Vydáno v:Bioinformatics
Hlavní autoři: Noh, Heeju, Gunawan, Rudiyanto
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937192/
https://ncbi.nlm.nih.gov/pubmed/27153589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw148
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