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TREAP: A New Topological Approach to Drug Target Inference
Over 50% of drugs fail in stage 3 clinical trials, many because of a poor understanding of the drug’s mechanisms of action (MoA). A better comprehension of drug MoA will significantly improve research and development (R&D). Current proposed algorithms, such as ProTINA and DeMAND, can be overly c...
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| Udgivet i: | Biophys J |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Biophysical Society
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7732766/ https://ncbi.nlm.nih.gov/pubmed/33129831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.10.021 |
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