Mapping human pluripotent stem cell differentiation pathways using high throughput single-cell RNA-sequencing

BACKGROUND: Human pluripotent stem cells (hPSCs) provide powerful models for studying cellular differentiations and unlimited sources of cells for regenerative medicine. However, a comprehensive single-cell level differentiation roadmap for hPSCs has not been achieved. RESULTS: We use high throughpu...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Genome Biol
Autori principali: Han, Xiaoping, Chen, Haide, Huang, Daosheng, Chen, Huidong, Fei, Lijiang, Cheng, Chen, Huang, He, Yuan, Guo-Cheng, Guo, Guoji
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887227/
https://ncbi.nlm.nih.gov/pubmed/29622030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1426-0
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