High-throughput karyotyping of human pluripotent stem cells

Genomic integrity of human pluripotent stem cell (hPSC) lines requires routine monitoring. We report here that novel karyotyping assay, utilizing bead-bound bacterial artificial chromosome probes, provides a fast and easy tool for detection of chromosomal abnormalities in hPSC lines. The analysis ca...

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Autors principals: Lund, Riikka J., Nikula, Tuomas, Rahkonen, Nelly, Närvä, Elisa, Baker, Duncan, Harrison, Neil, Andrews, Peter, Otonkoski, Timo, Lahesmaa, Riitta
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2012
Matèries:
Short Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502865/
https://ncbi.nlm.nih.gov/pubmed/22877823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2012.06.008
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