RNA Polymerase III Subunit POLR3G Regulates Specific Subsets of PolyA(+) and SmallRNA Transcriptomes and Splicing in Human Pluripotent Stem Cells

POLR3G is expressed at high levels in human pluripotent stem cells (hPSCs) and is required for maintenance of stem cell state through mechanisms not known in detail. To explore how POLR3G regulates stem cell state, we carried out deep-sequencing analysis of polyA(+) and smallRNA transcriptomes prese...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Principais autores: Lund, Riikka J., Rahkonen, Nelly, Malonzo, Maia, Kauko, Leni, Emani, Maheswara Reddy, Kivinen, Virpi, Närvä, Elisa, Kemppainen, Esko, Laiho, Asta, Skottman, Heli, Hovatta, Outi, Rasool, Omid, Nykter, Matti, Lähdesmäki, Harri, Lahesmaa, Riitta
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425787/
https://ncbi.nlm.nih.gov/pubmed/28494942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.04.016
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