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CRISPRi and CRISPRa screens in mammalian cells for precision biology and medicine

Next-generation DNA sequencing technologies have led to a massive accumulation of genomic and transcriptomic data from patients and healthy individuals. The major challenge ahead is to understand the functional significance of the elements of the human genome and transcriptome, and implications for...

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Detalles Bibliográficos
Publicado en:ACS Chem Biol
Autor Principal: Kampmann, Martin
Formato: Artigo
Idioma:Inglês
Publicado: 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886776/
https://ncbi.nlm.nih.gov/pubmed/29035510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00657
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