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CRISPRi and CRISPRa screens in mammalian cells for precision biology and medicine

Next-generation DNA sequencing technologies have led to a massive accumulation of genomic and transcriptomic data from patients and healthy individuals. The major challenge ahead is to understand the functional significance of the elements of the human genome and transcriptome, and implications for...

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Bibliografische gegevens
Gepubliceerd in:ACS Chem Biol
Hoofdauteur: Kampmann, Martin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886776/
https://ncbi.nlm.nih.gov/pubmed/29035510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00657
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