New factors for protein transport identified by a genome-wide CRISPRi screen in mammalian cells

Protein and membrane trafficking pathways are critical for cell and tissue homeostasis. Traditional genetic and biochemical approaches have shed light on basic principles underlying these processes. However, the list of factors required for secretory pathway function remains incomplete, and mechanis...

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Publicado en:J Cell Biol
Main Authors: Bassaganyas, Laia, Popa, Stephanie J., Horlbeck, Max, Puri, Claudia, Stewart, Sarah E., Campelo, Felix, Ashok, Anupama, Butnaru, Cristian M., Brouwers, Nathalie, Heydari, Kartoosh, Ripoche, Jean, Weissman, Jonathan, Rubinsztein, David C., Schekman, Randy, Malhotra, Vivek, Moreau, Kevin, Villeneuve, Julien
Formato: Artigo
Idioma:Inglês
Publicado: Rockefeller University Press 2019
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829651/
https://ncbi.nlm.nih.gov/pubmed/31488582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201902028
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