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Sodium channel TRPM4 and sodium/calcium exchangers (NCX) cooperate in the control of Ca(2+)-induced mucin secretion from goblet cells
Regulated mucin secretion is essential for the formation of the mucus layer that protects the underlying epithelial cells from foreign particles. Alterations in the quantity or quality of secreted mucins are therefore detrimental to airway and colon physiology. Based on various biochemical assays in...
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| Udgivet i: | J Biol Chem |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6341386/ https://ncbi.nlm.nih.gov/pubmed/30482841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000848 |
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