Sodium channel TRPM4 and sodium/calcium exchangers (NCX) cooperate in the control of Ca(2+)-induced mucin secretion from goblet cells

Regulated mucin secretion is essential for the formation of the mucus layer that protects the underlying epithelial cells from foreign particles. Alterations in the quantity or quality of secreted mucins are therefore detrimental to airway and colon physiology. Based on various biochemical assays in...

Full description

Saved in:
Bibliographic Details
Published in:J Biol Chem
Main Authors: Cantero-Recasens, Gerard, Butnaru, Cristian M., Brouwers, Nathalie, Mitrovic, Sandra, Valverde, Miguel A., Malhotra, Vivek
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2019
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341386/
https://ncbi.nlm.nih.gov/pubmed/30482841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000848
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items