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CRISPRi and CRISPRa screens in mammalian cells for precision biology and medicine

Next-generation DNA sequencing technologies have led to a massive accumulation of genomic and transcriptomic data from patients and healthy individuals. The major challenge ahead is to understand the functional significance of the elements of the human genome and transcriptome, and implications for...

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Bibliografiske detaljer
Udgivet i:ACS Chem Biol
Hovedforfatter: Kampmann, Martin
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886776/
https://ncbi.nlm.nih.gov/pubmed/29035510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00657
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