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Selective Covalent Protein Modification by 4-Halopyridines Through Catalysis
4-Halopyridines are developed herein as selective, tunable, and “switchable” covalent protein modifiers for use in the development of chemical probes. Non-enzymatic reactivity of 4-chloropyridine with amino acids and thiols is ranked with respect to common covalent protein modifying reagents and fou...
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| Publicado no: | Chembiochem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5886304/ https://ncbi.nlm.nih.gov/pubmed/28470883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201700104 |
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