Gene co-expression network analysis for identifying modules and functionally enriched pathways in SCA2

Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant neurodegenerative disease caused by CAG repeat expansion in the ATXN2 gene. The repeat resides in an encoded region of the gene resulting in polyglutamine (polyQ) expansion which has been assumed to result in gain of function, predominant...

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Veröffentlicht in:Hum Mol Genet
Hauptverfasser: Pflieger, Lance T., Dansithong, Warunee, Paul, Sharan, Scoles, Daniel R., Figueroa, Karla P., Meera, Pratap, Otis, Thomas S., Facelli, Julio C., Pulst, Stefan M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886232/
https://ncbi.nlm.nih.gov/pubmed/28525545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx191
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