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Co-expression networks in generation of induced pluripotent stem cells

We developed an adenoviral vector, in which Yamanaka's four reprogramming factors (RFs) were controlled by individual CMV promoters in a single cassette (Ad-SOcMK). This permitted coordinated expression of RFs (SOX2, OCT3/4, c-MYC and KLF4) in a cell for a transient period of time, synchronizin...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Paul, Sharan, Pflieger, Lance, Dansithong, Warunee, Figueroa, Karla P., Gao, Fuying, Coppola, Giovanni, Pulst, Stefan M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810748/
https://ncbi.nlm.nih.gov/pubmed/26892236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.016402
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