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Staufen1 links RNA stress granules and autophagy in a model of neurodegeneration
Spinocerebellar ataxia type 2 (SCA2) is a neurodegenerative disease caused by expansion of polyglutamine tract in the ATXN2 protein. We identified Staufen1 (STAU1) as an interactor of ATXN2, and showed elevation in cells from SCA2 patients, amyotrophic lateral sclerosis (ALS) patients, and in SCA2 m...
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| Gepubliceerd in: | Nat Commun |
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| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group UK
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6128856/ https://ncbi.nlm.nih.gov/pubmed/30194296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06041-3 |
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