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Gene co-expression network analysis for identifying modules and functionally enriched pathways in SCA2

Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant neurodegenerative disease caused by CAG repeat expansion in the ATXN2 gene. The repeat resides in an encoded region of the gene resulting in polyglutamine (polyQ) expansion which has been assumed to result in gain of function, predominant...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Pflieger, Lance T., Dansithong, Warunee, Paul, Sharan, Scoles, Daniel R., Figueroa, Karla P., Meera, Pratap, Otis, Thomas S., Facelli, Julio C., Pulst, Stefan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886232/
https://ncbi.nlm.nih.gov/pubmed/28525545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx191
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