COPD GWAS variant at 19q13.2 in relation with DNA methylation and gene expression

Chronic obstructive pulmonary disease (COPD) is among the major health burdens in adults. While cigarette smoking is the leading risk factor, a growing number of genetic variations have been discovered to influence disease susceptibility. Epigenetic modifications may mediate the response of the geno...

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發表在:Hum Mol Genet
Main Authors: Nedeljkovic, Ivana, Lahousse, Lies, Carnero-Montoro, Elena, Faiz, Alen, Vonk, Judith M, de Jong, Kim, van der Plaat, Diana A, van Diemen, Cleo C, van den Berge, Maarten, Obeidat, Ma’en, Bossé, Yohan, Nickle, David C, Consortium, B I O S, Uitterlinden, Andre G, van Meurs, Joyce B J, Stricker, Bruno H C, Brusselle, Guy G, Postma, Dirkje S, Boezen, H Marike, van Duijn, Cornelia M, Amin, Najaf
格式: Artigo
語言:Inglês
出版: Oxford University Press 2018
主題:
Association Studies Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886099/
https://ncbi.nlm.nih.gov/pubmed/29092026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx390
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