Understanding the role of the chromosome 15q25.1 in COPD through epigenetics and transcriptomics

Chronic obstructive pulmonary disease (COPD) is a major health burden in adults and cigarette smoking is considered the most important environmental risk factor of COPD. Chromosome 15q25.1 locus is associated with both COPD and smoking. Our study aims at understanding the mechanism underlying the as...

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Publicat a:Eur J Hum Genet
Autors principals: Nedeljkovic, Ivana, Carnero-Montoro, Elena, Lahousse, Lies, van der Plaat, Diana A., de Jong, Kim, Vonk, Judith M., van Diemen, Cleo C., Faiz, Alen, van den Berge, Maarten, Obeidat, Ma’en, Bossé, Yohan, Nickle, David C., Consortium, BIOS, Uitterlinden, Andre G., van Meurs, Joyce J. B., Stricker, Bruno C. H., Brusselle, Guy G., Postma, Dirkje S., Boezen, H. Marike, van Duijn, Cornelia M., Amin, Najaf
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945654/
https://ncbi.nlm.nih.gov/pubmed/29422661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-017-0089-8
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