Understanding the role of the chromosome 15q25.1 in COPD through epigenetics and transcriptomics

Chronic obstructive pulmonary disease (COPD) is a major health burden in adults and cigarette smoking is considered the most important environmental risk factor of COPD. Chromosome 15q25.1 locus is associated with both COPD and smoking. Our study aims at understanding the mechanism underlying the as...

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Publicado no:Eur J Hum Genet
Main Authors: Nedeljkovic, Ivana, Carnero-Montoro, Elena, Lahousse, Lies, van der Plaat, Diana A., de Jong, Kim, Vonk, Judith M., van Diemen, Cleo C., Faiz, Alen, van den Berge, Maarten, Obeidat, Ma’en, Bossé, Yohan, Nickle, David C., Consortium, BIOS, Uitterlinden, Andre G., van Meurs, Joyce J. B., Stricker, Bruno C. H., Brusselle, Guy G., Postma, Dirkje S., Boezen, H. Marike, van Duijn, Cornelia M., Amin, Najaf
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945654/
https://ncbi.nlm.nih.gov/pubmed/29422661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-017-0089-8
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