DNA methylation is associated with lung function in never smokers

BACKGROUND: Active smoking is the main risk factor for COPD. Here, epigenetic mechanisms may play a role, since cigarette smoking is associated with differential DNA methylation in whole blood. So far, it is unclear whether epigenetics also play a role in subjects with COPD who never smoked. Therefo...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: de Vries, Maaike, Nedeljkovic, Ivana, van der Plaat, Diana A., Zhernakova, Alexandra, Lahousse, Lies, Brusselle, Guy G., Amin, Najaf, van Duijn, Cornelia M., Vonk, Judith M., Boezen, H. Marike
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889726/
https://ncbi.nlm.nih.gov/pubmed/31791327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-019-1222-8
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