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A Genome-Wide Linkage Study for Chronic Obstructive Pulmonary Disease in a Dutch Genetic Isolate Identifies Novel Rare Candidate Variants

Chronic obstructive pulmonary disease (COPD) is a complex and heritable disease, associated with multiple genetic variants. Specific familial types of COPD may be explained by rare variants, which have not been widely studied. We aimed to discover rare genetic variants underlying COPD through a geno...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Nedeljkovic, Ivana, Terzikhan, Natalie, Vonk, Judith M., van der Plaat, Diana A., Lahousse, Lies, van Diemen, Cleo C., Hobbs, Brian D., Qiao, Dandi, Cho, Michael H., Brusselle, Guy G., Postma, Dirkje S., Boezen, H. M., van Duijn, Cornelia M., Amin, Najaf
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916965/
https://ncbi.nlm.nih.gov/pubmed/29725345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00133
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