Genetic analysis of Wnt/PCP genes in neural tube defects

BACKGROUND: Mouse homozygous mutants in Wnt/planar cell polarity (PCP) pathway genes have been shown to cause neural tube defects (NTDs) through the disruption of normal morphogenetic processes critical to neural tube closure (NTC). Knockout mice that are heterozygotes of single PCP genes likely fai...

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Bibliografiske detaljer
Udgivet i:BMC Med Genomics
Main Authors: Chen, Zhongzhong, Lei, Yunping, Cao, Xuanye, Zheng, Yufang, Wang, Fang, Bao, Yihua, Peng, Rui, Finnell, Richard H., Zhang, Ting, Wang, Hongyan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885375/
https://ncbi.nlm.nih.gov/pubmed/29618362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-018-0355-9
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