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Genetic analysis of Wnt/PCP genes in neural tube defects
BACKGROUND: Mouse homozygous mutants in Wnt/planar cell polarity (PCP) pathway genes have been shown to cause neural tube defects (NTDs) through the disruption of normal morphogenetic processes critical to neural tube closure (NTC). Knockout mice that are heterozygotes of single PCP genes likely fai...
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| Publicado no: | BMC Med Genomics |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5885375/ https://ncbi.nlm.nih.gov/pubmed/29618362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-018-0355-9 |
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