Genetic analysis of Wnt/PCP genes in neural tube defects

BACKGROUND: Mouse homozygous mutants in Wnt/planar cell polarity (PCP) pathway genes have been shown to cause neural tube defects (NTDs) through the disruption of normal morphogenetic processes critical to neural tube closure (NTC). Knockout mice that are heterozygotes of single PCP genes likely fai...

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Bibliografske podrobnosti
izdano v:BMC Med Genomics
Main Authors: Chen, Zhongzhong, Lei, Yunping, Cao, Xuanye, Zheng, Yufang, Wang, Fang, Bao, Yihua, Peng, Rui, Finnell, Richard H., Zhang, Ting, Wang, Hongyan
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885375/
https://ncbi.nlm.nih.gov/pubmed/29618362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-018-0355-9
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