Genetic analysis of Wnt/PCP genes in neural tube defects

BACKGROUND: Mouse homozygous mutants in Wnt/planar cell polarity (PCP) pathway genes have been shown to cause neural tube defects (NTDs) through the disruption of normal morphogenetic processes critical to neural tube closure (NTC). Knockout mice that are heterozygotes of single PCP genes likely fai...

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Vydáno v:BMC Med Genomics
Hlavní autoři: Chen, Zhongzhong, Lei, Yunping, Cao, Xuanye, Zheng, Yufang, Wang, Fang, Bao, Yihua, Peng, Rui, Finnell, Richard H., Zhang, Ting, Wang, Hongyan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885375/
https://ncbi.nlm.nih.gov/pubmed/29618362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-018-0355-9
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