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Acetaminophen Toxicity: Novel Insights Into Mechanisms and Future Perspectives

Acetaminophen (APAP) overdose is the most common cause of acute liver failure in the US, and decades of intense study of its pathogenesis resulted in the development of the antidote N-acetylcysteine, which facilitates scavenging of the reactive metabolite and is the only treatment in clinical use. H...

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Dettagli Bibliografici
Pubblicato in:Gene Expr
Autori principali: Ramachandran, Anup, Jaeschke, Hartmut
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cognizant Communication Corporation 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885144/
https://ncbi.nlm.nih.gov/pubmed/29054140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/105221617X15084371374138
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