Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent responses

Inflammation is an established contributor to disease and the NLRP3 inflammasome is emerging as a potential therapeutic target. A number of small molecule inhibitors of the NLRP3 pathway have been described. Here we analysed the most promising of these inhibitor classes side by side to assess relati...

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Publicat a:Sci Rep
Autors principals: Redondo-Castro, Elena, Faust, Dorte, Fox, Simon, Baldwin, Alex G., Osborne, Simon, Haley, Michael J., Karran, Eric, Nuthall, Hugh, Atkinson, Peter J., Dawson, Lee A., Routledge, Carol, Allan, Stuart M., Freeman, Sally, Brownlees, Janet, Brough, David
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884858/
https://ncbi.nlm.nih.gov/pubmed/29618797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24029-3
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