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An immuno-assay to quantify influenza virus hemagglutinin with correctly folded stalk domains in vaccine preparations

The standard method to quantify the hemagglutinin content of influenza virus vaccines is the single radial immunodiffusion assay. This assay primarily relies on polyclonal antibodies against the head domain of the influenza virus hemagglutinin, which is the main target antigen of influenza virus vac...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Rajendran, Madhusudan, Sun, Weina, Comella, Phillip, Nachbagauer, Raffael, Wohlbold, Teddy John, Amanat, Fatima, Kirkpatrick, Ericka, Palese, Peter, Krammer, Florian
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884525/
https://ncbi.nlm.nih.gov/pubmed/29617394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194830
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