Puromycin A, B and C, cryptic nucleosides identified from Streptomyces alboniger NRRL B-1832 by PPtase-based activation

Natural product discovery is pivot for drug development, however, this endeavor is often challenged by the wide inactivation or silence of natural products biosynthetic pathways. We recently developed a highly efficient approach to activate cryptic/silenced biosynthetic pathways through augmentation...

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Bibliografiska uppgifter
I publikationen:Synth Syst Biotechnol
Huvudupphovsmän: Yan, Xiaoli, Zhang, Benyin, Tian, Wenya, Dai, Qi, Zheng, Xiaoqin, Hu, Ke, Liu, Xinxin, Deng, Zixin, Qu, Xudong
Materialtyp: Artigo
Språk:Inglês
Publicerad: KeAi Publishing 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884247/
https://ncbi.nlm.nih.gov/pubmed/29911201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.synbio.2018.02.001
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