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Biosynthesis of the β-Methylarginine Residue of Peptidyl Nucleoside Arginomycin in Streptomyces arginensis NRRL 15941

The peptidyl nucleoside arginomycin is active against Gram-positive bacteria and fungi but displays much lower toxicity to mice than its analog blasticidin S. It features a rare amino acid, β-methylarginine, which is attached to the deoxyhexose moiety via a 4′-aminoacyl bond. We here report cloning...

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Detalhes bibliográficos
Main Authors: Feng, Jun, Wu, Jun, Gao, Jie, Xia, Zhigui, Deng, Zixin, He, Xinyi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135772/
https://ncbi.nlm.nih.gov/pubmed/24907335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01172-14
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