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Puromycin A, B and C, cryptic nucleosides identified from Streptomyces alboniger NRRL B-1832 by PPtase-based activation
Natural product discovery is pivot for drug development, however, this endeavor is often challenged by the wide inactivation or silence of natural products biosynthetic pathways. We recently developed a highly efficient approach to activate cryptic/silenced biosynthetic pathways through augmentation...
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| Udgivet i: | Synth Syst Biotechnol |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
KeAi Publishing
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5884247/ https://ncbi.nlm.nih.gov/pubmed/29911201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.synbio.2018.02.001 |
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