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Characterization of an A-Site Selective Protein Disulfide Isomerase A1 Inhibitor
Protein disulfide isomerase A1 (PDIA1) is an endoplasmic reticulum (ER)-localized thiol-disulfide oxidoreductase that is an important folding catalyst for secretory pathway proteins. PDIA1 contains two active-site domains (a and a′), each containing a Cys-Gly-His-Cys (CGHC) active-site motif. The tw...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5884060/ https://ncbi.nlm.nih.gov/pubmed/29521097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00178 |
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