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Characterization of the Estradiol-Binding Site Structure of Human Protein Disulfide Isomerase (PDI)
BACKGROUND: Earlier studies showed that 17β-estradiol (E(2)), an endogenous female sex hormone, can bind to human protein disulfide isomerase (PDI), a protein folding catalyst for disulfide bond formation and rearrangement. This binding interaction can modulate the intracellular levels of E(2) and i...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Public Library of Science
2011
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3207843/ https://ncbi.nlm.nih.gov/pubmed/22073283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027185 |
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