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Challenges in the evaluation of thiol-reactive inhibitors of human protein disulfide isomerase

This paper addresses how to evaluate the efficacy of the growing inventory of thiol-reactive inhibitors of mammalian protein disulfide isomerase (PDI) enzymes under realistic concentrations of potentially competing thiol-containing peptides and proteins. For this purpose, we introduce a variant of t...

詳細記述

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書誌詳細
出版年:Free Radic Biol Med
主要な著者: Foster, Celia K., Thorpe, Colin
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507595/
https://ncbi.nlm.nih.gov/pubmed/28465261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.04.367
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