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Intrinsically Disordered Protein Exhibits Both Compaction and Expansion under Macromolecular Crowding

Conformational malleability allows intrinsically disordered proteins (IDPs) to respond agilely to their environments, such as nonspecifically interacting with in vivo bystander macromolecules (or crowders). Previous studies have emphasized conformational compaction of IDPs due to steric repulsion by...

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Détails bibliographiques
Publié dans:Biophys J
Auteurs principaux: Banks, Anthony, Qin, Sanbo, Weiss, Kevin L., Stanley, Christopher B., Zhou, Huan-Xiang
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883552/
https://ncbi.nlm.nih.gov/pubmed/29539394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.01.011
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