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A Generalized Fundamental Measure Theory for Atomistic Modeling of Macromolecular Crowding

Macromolecular crowding inside cells affects the thermodynamic and kinetic properties of proteins. The scaled particle theory (SPT) has played an important role toward establishing a qualitative picture for the effects of crowding. However, SPT-based modeling lacks molecular details. Molecular dynam...

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Autori principali: Qin, Sanbo, Zhou, Huan-Xiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537823/
https://ncbi.nlm.nih.gov/pubmed/20365782
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