Atomistic Modeling of Macromolecular Crowding Predicts Modest Increases in Protein Folding and Binding Stability

Theoretical models predict that macromolecular crowding can increase protein folding stability, but depending on details of the models (e.g., how the denatured state is represented), the level of stabilization predicted can be very different. In this study, we represented the native and denatured st...

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Bibliographic Details
Main Authors: Qin, Sanbo, Zhou, Huan-Xiang
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2009
Subjects:
Biophysical Theory and Modeling
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711389/
https://ncbi.nlm.nih.gov/pubmed/19580740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.03.066
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