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Atomistic Modeling of Macromolecular Crowding Predicts Modest Increases in Protein Folding and Binding Stability

Theoretical models predict that macromolecular crowding can increase protein folding stability, but depending on details of the models (e.g., how the denatured state is represented), the level of stabilization predicted can be very different. In this study, we represented the native and denatured st...

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Bibliografiska uppgifter
Huvudupphovsmän: Qin, Sanbo, Zhou, Huan-Xiang
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Biophysical Society 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711389/
https://ncbi.nlm.nih.gov/pubmed/19580740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.03.066
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