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Atomistic Modeling of Macromolecular Crowding Predicts Modest Increases in Protein Folding and Binding Stability

Theoretical models predict that macromolecular crowding can increase protein folding stability, but depending on details of the models (e.g., how the denatured state is represented), the level of stabilization predicted can be very different. In this study, we represented the native and denatured st...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Qin, Sanbo, Zhou, Huan-Xiang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711389/
https://ncbi.nlm.nih.gov/pubmed/19580740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.03.066
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