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Atomistic Modeling of Macromolecular Crowding Predicts Modest Increases in Protein Folding and Binding Stability

Theoretical models predict that macromolecular crowding can increase protein folding stability, but depending on details of the models (e.g., how the denatured state is represented), the level of stabilization predicted can be very different. In this study, we represented the native and denatured st...

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מידע ביבליוגרפי
Main Authors: Qin, Sanbo, Zhou, Huan-Xiang
פורמט: Artigo
שפה:Inglês
יצא לאור: The Biophysical Society 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711389/
https://ncbi.nlm.nih.gov/pubmed/19580740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.03.066
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