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Effect of Macromolecular Crowding on Protein Binding Stability: Modest Stabilization and Significant Biological Consequences
Macromolecular crowding has long been known to significantly affect protein oligomerization, and yet no direct quantitative measurements appear to have been made of its effects on the binding free energy of the elemental step of adding a single subunit. Here, we report the effects of two crowding ag...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Biophysical Society
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2718143/ https://ncbi.nlm.nih.gov/pubmed/19651049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.05.032 |
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