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Effects of macromolecular crowding on protein conformational changes.

Many protein functions can be directly linked to conformational changes. Inside cells, the equilibria and transition rates between different conformations may be affected by macromolecular crowding. We have recently developed a new approach for modeling crowding effects, which enables an atomistic r...

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Detalhes bibliográficos
Main Authors: Hao Dong, Sanbo Qin, Huan-Xiang Zhou
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2010-07-01
Colecção:PLoS Computational Biology
Acesso em linha:http://europepmc.org/articles/PMC2895631?pdf=render
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