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MeCP2-mediated epigenetic regulation in senescent endothelial progenitor cells

BACKGROUND: Cellular aging may be associated with epigenetics. Methyl-CpG-binding protein 2 (MeCP2) and sirtuin 1 (SIRT1) are two important epigenetic factors. Our former work demonstrated that MeCP2 expression increased and SIRT1 expression decreased in senescent endothelial progenitor cells (EPCs)...

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Bibliografiske detaljer
Udgivet i:Stem Cell Res Ther
Main Authors: Wang, Chunli, Wang, Fei, Li, Zhen, Cao, Qing, Huang, Liya, Chen, Shuyan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883541/
https://ncbi.nlm.nih.gov/pubmed/29615114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-0828-y
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