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MeCP2 inhibits cell functionality through FoxO3a and autophagy in endothelial progenitor cells

Objectives: Autophagy is an evolutionarily conserved intracellular degradation mechanism in which cell constituents are phagocytosed to maintain cellular homeostasis. Forkhead box O 3a (FoxO3a) promotes autophagy to protect cells from environmental stress. Methylated CpG binding protein 2 (MeCP2) is...

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Pubblicato in:Aging (Albany NY)
Autori principali: Zha, Siyuan, Li, Zhen, Chen, Shuyan, Liu, Fang, Wang, Fei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756911/
https://ncbi.nlm.nih.gov/pubmed/31477637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102183
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