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Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copy-number driven cancers

To realize the full potential of immunotherapy, it is critical to understand the drivers of tumor infiltration by immune cells. Previous studies have linked immune infiltration with tumor neoantigen levels, but the broad applicability of this concept remains unknown. Here, we find that while this ob...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: McGrail, Daniel J., Federico, Lorenzo, Li, Yongsheng, Dai, Hui, Lu, Yiling, Mills, Gordon B., Yi, Song, Lin, Shiaw-Yih, Sahni, Nidhi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882811/
https://ncbi.nlm.nih.gov/pubmed/29615613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03730-x
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