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Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copy-number driven cancers

To realize the full potential of immunotherapy, it is critical to understand the drivers of tumor infiltration by immune cells. Previous studies have linked immune infiltration with tumor neoantigen levels, but the broad applicability of this concept remains unknown. Here, we find that while this ob...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: McGrail, Daniel J., Federico, Lorenzo, Li, Yongsheng, Dai, Hui, Lu, Yiling, Mills, Gordon B., Yi, Song, Lin, Shiaw-Yih, Sahni, Nidhi
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882811/
https://ncbi.nlm.nih.gov/pubmed/29615613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03730-x
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