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Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copy-number driven cancers

To realize the full potential of immunotherapy, it is critical to understand the drivers of tumor infiltration by immune cells. Previous studies have linked immune infiltration with tumor neoantigen levels, but the broad applicability of this concept remains unknown. Here, we find that while this ob...

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Vydáno v:Nat Commun
Hlavní autoři: McGrail, Daniel J., Federico, Lorenzo, Li, Yongsheng, Dai, Hui, Lu, Yiling, Mills, Gordon B., Yi, Song, Lin, Shiaw-Yih, Sahni, Nidhi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882811/
https://ncbi.nlm.nih.gov/pubmed/29615613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03730-x
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