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Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copy-number driven cancers

To realize the full potential of immunotherapy, it is critical to understand the drivers of tumor infiltration by immune cells. Previous studies have linked immune infiltration with tumor neoantigen levels, but the broad applicability of this concept remains unknown. Here, we find that while this ob...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: McGrail, Daniel J., Federico, Lorenzo, Li, Yongsheng, Dai, Hui, Lu, Yiling, Mills, Gordon B., Yi, Song, Lin, Shiaw-Yih, Sahni, Nidhi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882811/
https://ncbi.nlm.nih.gov/pubmed/29615613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03730-x
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